Dissecting the Genetic Complexity of the Association between Human Leukocyte Antigens and Rheumatoid Arthritis
نویسندگان
چکیده
منابع مشابه
Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis.
Rheumatoid arthritis (RA) is an inflammatory disease with a complex genetic component. An association between RA and the human leukocyte antigen (HLA) complex has long been observed in many different populations, and most studies have focused on a direct role for the HLA-DRB1 "shared epitope" in disease susceptibility. We have performed an extensive haplotype analysis, using 54 markers distribu...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2002
ISSN: 0002-9297
DOI: 10.1086/342407